Suppressors
نویسندگان
چکیده
منابع مشابه
Tumor suppressors: enhancers or suppressors of regeneration?
Tumor suppressors are so named because cancers occur in their absence, but these genes also have important functions in development, metabolism and tissue homeostasis. Here, we discuss known and potential functions of tumor suppressor genes during tissue regeneration, focusing on the evolutionarily conserved tumor suppressors pRb1, p53, Pten and Hippo. We propose that their activity is essentia...
متن کاملInteraction of UAG suppressors and omnipotent suppressors in Saccharomyces cerevisiae.
Haploids bearing the dominant UAG suppressor, SUP7-a, and various alleles of the omnipotent suppressor sup35 were examined. The presence of the UAG suppressor reduced the efficiency of some alleles of sup35, and caused other sup35 alleles to be lethal. A nonclassical interaction of the dominant suppressor tRNA and the ribosome is proposed to explain these observations.
متن کاملNovel nematode amber suppressors.
Nine amber suppressor mutations were isolated in the nematode Caenorhabditis elegans by reverting amber alleles of a sex-determining gene, tra-3. One suppressor maps to a known locus, sup-5 III , but the other eight map to three new loci, sup-21 X (five alleles), sup-22 IV (two alleles) and sup-23 IV (one allele). Amber alleles of tra-3 and of a dumpy gene, dpy-20, were used to measure the effi...
متن کاملOncogenes and Tumor Suppressors
Our understanding of estrogen (17b-estradiol, E2) receptor biology has evolved in recent years with the discovery and characterization of a 7-transmembrane-spanning G protein–coupled estrogen receptor (GPER/GPR30) and the development of GPER-selective functional chemical probes. GPER is highly expressed in certain breast, endometrial, and ovarian cancers, establishing the importance of noninvas...
متن کاملSurge Suppressors and Clamps
A tutorial paper with a review of the technologies available in the mid-eighties for surge protection of lowvoltage end-user equipment. The principles of operation are described for “crowbar devices” (now generally described under the standardized name of “voltage switching devices”) and for “voltage clamping devices: (now generally described under the standardized name of “voltage limiting dev...
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ژورنال
عنوان ژورنال: Fungal Genetics Reports
سال: 1969
ISSN: 1941-4765
DOI: 10.4148/1941-4765.2048